解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::Many sensory brain regions are characterized by extensive local network interactions. However, we know relatively little about the contribution of this microcircuitry to sensory coding. Detailed analyses of neuronal microcircuitry are usually performed in vitro, whereas sensory processing is typically studied by recor...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00145.2013
更新日期:2013-07-01 00:00:00
abstract::Inner ear hair cell afferent fiber synapses are capable of transferring information at high rates for long periods of time with extraordinary fidelity. As at other sensory synapses, hair cells rely on graded receptor potentials and unique vesicle trafficking and release properties of ribbon synapses to relay intensity...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00121.2013
更新日期:2013-07-01 00:00:00
abstract::The mechanisms behind the therapeutic effects of electrical stimulation of the brain in epilepsy and other disorders are poorly understood. Previous studies in vitro have shown that uniform electric fields can suppress epileptiform activity through a direct polarizing effect on neuronal membranes. Such an effect depen...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00887.2012
更新日期:2013-06-01 00:00:00
abstract::The development of auditory temporal processing is important for processing complex sounds as well as for acquiring reading and language skills. Neuronal properties and sound processing change dramatically in auditory cortex neurons after the onset of hearing. However, the development of the auditory thalamus or media...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00021.2013
更新日期:2013-06-01 00:00:00
abstract::Exercise, in the form of moderate daily treadmill training following nerve transection and repair leads to enhanced axon regeneration, but its effect on functional recovery is less well known. Female rats were exercised by walking continuously, at a slow speed (10 m/min), for 1 h/day on a level treadmill, beginning 3 ...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00946.2012
更新日期:2013-06-01 00:00:00
abstract::In this paper, the predictive capability of surface and untargeted intramuscular electromyography (EMG) was compared with respect to wrist-joint torque to quantify which type of measurement better represents joint torque during multiple degrees-of-freedom (DoF) movements for possible application in prosthetic control....
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00086.2013
更新日期:2013-06-01 00:00:00
abstract::A desirable goal of functional MRI (fMRI), both clinically and for basic research, is to produce detailed maps of cortical function in individual subjects. Single-subject mapping of the somatotopic hand representation in the human primary somatosensory cortex (S1) has been performed using both phase-encoding and block...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00499.2012
更新日期:2013-05-01 00:00:00
abstract::The cardiac ganglion (CG) of Homarus americanus is a central pattern generator that consists of two oscillatory groups of neurons: "small cells" (SCs) and "large cells" (LCs). We have shown that SCs and LCs begin their bursts nearly simultaneously but end their bursts at variable phases. This variability contrasts wit...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.01010.2012
更新日期:2013-05-01 00:00:00
abstract::Human languages can express opposite propositions by means of the negative operator "not," which turns affirmative sentences into negative ones. Psycholinguistic research has indicated that negative meanings are formed by transiently reducing the access to mental representations of negated conceptual information. Neur...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00894.2012
更新日期:2013-04-01 00:00:00
abstract::The responsiveness of sensory neurons to muscle metabolites is altered under the conditions of insufficient limb blood supply in some diseases, such as peripheral artery disease. The purpose of this study was to examine ATP-induced current with activation of purinergic P2X subtypes P2X₃ and P2X₂/₃ in dorsal root gangl...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.01068.2012
更新日期:2013-04-01 00:00:00
abstract::Epiretinal implants for the blind are designed to stimulate surviving retinal neurons, thus bypassing the diseased photoreceptor layer. Single-unit or multielectrode recordings from isolated animal retina are commonly used to inform the design of these implants. However, such electrical recordings provide limited info...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00852.2012
更新日期:2013-04-01 00:00:00
abstract::Saccade adaptation is a mechanism that adjusts saccade landing positions if they systematically fail to reach their intended target. In the laboratory, saccades can be shortened or lengthened if the saccade target is displaced during execution of the saccade. In this study, saccades were performed from different posit...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00743.2012
更新日期:2013-04-01 00:00:00
abstract::Many critically ill patients in intensive care units suffer from an infection-induced whole body inflammatory state known as sepsis, which causes severe weakness in patients who survive. The mechanisms by which sepsis triggers intensive care unit-acquired weakness (ICUAW) remain unclear. Currently, research into ICUAW...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00936.2012
更新日期:2013-04-01 00:00:00
abstract::This study aimed to determine whether individuals with spastic diplegic cerebral palsy (SDCP) have deficits in anticipatory inhibition of postural muscle activity. Nine individuals with SDCP (SDCP group, 3 female and 6 male, 13-24 yr of age) and nine age- and sex-matched individuals without disability (control group) ...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00253.2012
更新日期:2013-04-01 00:00:00
abstract::Numerous developmental changes in the nervous system occur during the first several weeks of the rodent lifespan. Therefore, many characteristics of neuronal function described at the cellular level from in vitro slice experiments conducted during this early time period may not generalize to adult ages. We investigate...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00756.2012
更新日期:2013-03-01 00:00:00
abstract::Whenever the eyes move, spatial attention must keep track of the locations of targets as they shift on the retina. This study investigated transsaccadic updating of visual attention to cued targets. While observers prepared a saccade, we flashed an irrelevant, but salient, color cue in their visual periphery and measu...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00656.2012
更新日期:2013-03-01 00:00:00
abstract::Using near-infrared spectroscopy (NIRS) and multichannel probes, we studied hemoglobin (Hb) concentration changes when single-pulse transcranial magnetic stimulation (TMS) was applied over the left hemisphere primary motor cortex (M1). Seventeen measurement probes were centered over left M1. Subjects were studied in b...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00980.2011
更新日期:2013-03-01 00:00:00
abstract::The execution of action sequences is the basis of most behavior. However, little is known about the neural foundation of visuomotor sequence execution in birds, although pigeons are a classic model animal to study sequence learning and production. Recently, we identified two structures in the pigeon brain, the nidopal...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00763.2012
更新日期:2013-02-01 00:00:00
abstract::Bladder and erectile dysfunction are common urologic complications of diabetes and are associated with reduced parasympathetic autonomic control. To determine whether disruption of ganglionic neurotransmission contributes to the loss of function, we investigated synaptic transmission at parasympathetic, major pelvic g...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00354.2012
更新日期:2013-02-01 00:00:00
abstract::The cerebellum has long been recognized to play an important role in motor adaptation. Individuals with cerebellar ataxia exhibit impaired learning in visuomotor adaptation tasks such as prism adaptation and force field learning. Both types of tasks involve the adjustment of an internal model to compensate for an exte...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00654.2011
更新日期:2013-02-01 00:00:00
abstract::Skin on the foot sole plays an important role in postural control. Cooling the skin of the foot is often used to induce anesthesia to determine the role of skin in motor and balance control. The effect of cooling on the four classes of mechanoreceptor in the skin is largely unknown, and thus the aim of the present stu...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00381.2012
更新日期:2013-02-01 00:00:00
abstract::Previous research using a loud acoustic stimulus (LAS) to investigate motor preparation in reaction time (RT) tasks indicates that responses can be triggered well in advance of the presentation of an imperative stimulus (IS). This is intriguing given that high levels of response preparation cannot be maintained for lo...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.01119.2011
更新日期:2013-02-01 00:00:00
abstract::Subacute and chronic changes in tonic GABAergic inhibition occur in human and experimental epilepsy. Less is known about how tonic inhibition is modulated over shorter time frames (seconds). We measured endogenous tonic GABA currents from cultured rat hippocampal neurons to evaluate how they are affected by 1) transie...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00460.2012
更新日期:2013-02-01 00:00:00
abstract::Increasing evidence demonstrates that modulating the cGMP-dependent protein kinase G (PKG) pathway produces an array of behavioral phenotypes in the fruit fly, Drosophila melanogaster. Altering PKG activity, either genetically via the foraging (for) gene or using pharmacology modifies tolerance to acute abiotic stress...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00784.2011
更新日期:2013-02-01 00:00:00
abstract::In the auditory system of the big brown bat (Eptesicus fuscus), paired conditioned tonal (CS) and unconditioned leg stimuli (US) for auditory fear conditioning elicit tone-specific plasticity represented by best-frequency (BF) shifts that are augmented by acetylcholine, whereas unpaired CS and US for pseudoconditionin...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00930.2011
更新日期:2013-02-01 00:00:00
abstract::The temporal lobe is well known for its oscillatory activity associated with exploration, navigation, and learning. Intrinsic membrane potential oscillations (MPOs) and resonance of stellate cells (SCs) in layer II of the entorhinal cortex are thought to contribute to network oscillations and thereby to the encoding o...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00743.2011
更新日期:2013-01-01 00:00:00
abstract::Event-related potentials (ERPs) have provided crucial data concerning the time course of psychological processes, but the neural mechanisms producing ERP components remain poorly understood. This study continues a program of research in which we investigated the neural basis of attention-related ERP components by simu...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00549.2012
更新日期:2013-01-01 00:00:00
abstract::Falls during walking are a major cause of poststroke injury, and walking faster may decrease the ability to recover following a gait perturbation. We compared gait stability between high-functioning poststroke individuals and controls and evaluated the effect of gait speed on gait stability. Ten stroke subjects and te...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00552.2012
更新日期:2013-01-01 00:00:00
abstract::It is often suggested that decisions are made when accumulated sensory information reaches a fixed accuracy criterion. This is supported by many studies showing a gradual build up of neural activity to a threshold. However, the proposal that this build up is caused by sensory accumulation is challenged by findings tha...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.01071.2011
更新日期:2012-12-01 00:00:00
abstract::Recent work has investigated the link between motor learning and sensory function in arm movement control. A number of findings are consistent with the idea that motor learning is associated with systematic changes to proprioception (Haith A, Jackson C, Mial R, Vijayakumar S. Adv Neural Inf Process Syst 21: 593-600, 2...
journal_title:Journal of neurophysiology
pub_type: 杂志文章,随机对照试验
doi:10.1152/jn.00122.2012
更新日期:2012-12-01 00:00:00
abstract::The relationship between neck muscle electromyography (EMG) and torsional head rotation (about the nasooccipital axis) is difficult to assess during normal gaze behaviors with the head upright. Here, we induced acute head tilts similar to cervical dystonia (torticollis) in two monkeys by electrically stimulating 20 in...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00312.2012
更新日期:2012-12-01 00:00:00
abstract::The mouse is an important model system for investigating the neural circuits mediating behavior. Because of advances in imaging and optogenetic methods, head-fixed mouse preparations provide an unparalleled opportunity to observe and control neural circuits. To investigate how neural circuits produce behavior, these m...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00669.2012
更新日期:2012-12-01 00:00:00
abstract::Respiratory depression is a therapy-limiting side effect of opioid analgesics, yet our understanding of the brain circuits mediating this potentially lethal outcome remains incomplete. Here we studied the contribution of the rostral ventromedial medulla (RVM), a region long implicated in pain modulation and homeostati...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00563.2012
更新日期:2012-11-01 00:00:00
abstract::Noninvasive alternating current stimulation can induce vision restoration in patients with chronic optic nerve damage and results in electroencephalogram (EEG) aftereffects. To better understand the mechanisms of action, we studied such EEG "aftereffects" of transcorneal alternating current stimulation (tACS) at the c...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00341.2012
更新日期:2012-11-01 00:00:00
abstract::The intrinsic properties of tonically firing neurons in the cochlear nucleus contribute to representing average sound intensity by favoring synaptic integration across auditory nerve inputs, reducing phase locking to fine temporal acoustic structure and enhancing envelope locking. To determine whether tonically firing...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00092.2012
更新日期:2012-11-01 00:00:00
abstract::Internally generated, spontaneous activity is ubiquitous in the cortex, yet it does not appear to have a significant negative impact on sensory processing. Various studies have found that stimulus onset reduces the variability of cortical responses, but the characteristics of this suppression remained unexplored. By r...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00723.2011
更新日期:2012-11-01 00:00:00
abstract::Humans adopt very different head movement strategies for different gaze behaviors, for example, when playing sports versus watching sports on television. Such strategy switching appears to depend on both context and expectation of future gaze positions. Here, we explored the neural mechanisms for such behaviors by tra...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00222.2012
更新日期:2012-11-01 00:00:00
abstract::Properties, developmental regulation, and cAMP modulation of the hyperpolarization-activated current (I(h)) were investigated by the whole cell patch-clamp technique in vestibular ganglion neurons of the rat at two postnatal stages (P7-10 and P25-28). In addition, by RT-PCR and immunohistochemistry the identity and di...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00337.2012
更新日期:2012-10-01 00:00:00
abstract::Certain hand-held tools alter the mapping between hand motion and motion of the tool end point that must be controlled in order to perform a task. For example, when using a pool cue, the motion of the cue tip is reversed relative to the hand. Previous studies have shown that the time required to initiate a reaching mo...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00157.2012
更新日期:2012-10-01 00:00:00
abstract::Synchronous neural oscillations are found throughout the brain and are thought to contribute to neural coding and the propagation of activity. Several proposed mechanisms of synchronization have gained support through combined theoretical and experimental investigation, including mechanisms based on coupling and corre...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00362.2012
更新日期:2012-10-01 00:00:00